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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNKS2
All Species:
15.45
Human Site:
S849
Identified Species:
28.33
UniProt:
Q9H2K2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2K2
NP_079511.1
1166
126918
S849
D
N
L
S
G
S
F
S
E
L
S
S
V
V
S
Chimpanzee
Pan troglodytes
XP_001137443
1327
142033
A1007
A
E
L
A
V
G
G
A
S
N
A
G
D
G
A
Rhesus Macaque
Macaca mulatta
XP_001090358
1327
142132
A1007
A
E
L
A
V
G
G
A
S
N
A
G
D
G
A
Dog
Lupus familis
XP_534962
1316
141794
S999
D
N
L
S
G
S
F
S
E
L
S
S
V
V
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_001157107
1166
126725
S849
D
N
L
S
G
S
F
S
E
L
S
A
V
V
S
Rat
Rattus norvegicus
NP_001101077
1166
126761
S849
D
N
L
A
G
S
F
S
E
L
S
A
V
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508887
1320
142724
A1000
S
E
L
A
V
G
G
A
S
N
A
G
D
G
A
Chicken
Gallus gallus
Q5F478
990
107379
A695
E
K
E
A
S
V
D
A
A
D
L
L
G
C
T
Frog
Xenopus laevis
NP_001088420
1303
140252
V983
A
E
L
A
V
G
G
V
S
N
A
G
D
G
A
Zebra Danio
Brachydanio rerio
Q502K3
1071
114412
S750
S
R
D
F
Q
G
R
S
A
L
H
L
A
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651410
1181
127927
L843
P
T
T
E
T
V
L
L
P
T
G
A
S
M
I
Honey Bee
Apis mellifera
XP_396483
1166
127309
S848
C
V
P
L
A
R
P
S
S
C
L
S
P
M
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186587
1157
126547
G852
G
Q
P
V
Q
V
D
G
G
I
Q
F
E
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.5
72.5
87.9
N.A.
97.2
97.2
N.A.
72.5
24
73.1
23.3
N.A.
65.3
70.6
N.A.
69.5
Protein Similarity:
100
80.3
80.3
88.2
N.A.
98.8
99
N.A.
80.5
40.3
81.3
38.9
N.A.
79.8
83
N.A.
83.1
P-Site Identity:
100
6.6
6.6
100
N.A.
93.3
86.6
N.A.
6.6
0
6.6
20
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
33.3
33.3
100
N.A.
100
100
N.A.
33.3
26.6
26.6
20
N.A.
13.3
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
47
8
0
0
31
16
0
31
24
8
8
31
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% C
% Asp:
31
0
8
0
0
0
16
0
0
8
0
0
31
0
0
% D
% Glu:
8
31
8
8
0
0
0
0
31
0
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
0
31
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
0
31
39
31
8
8
0
8
31
8
31
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
62
8
0
0
8
8
0
39
16
16
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
0
31
0
0
0
0
0
0
0
31
0
0
0
0
0
% N
% Pro:
8
0
16
0
0
0
8
0
8
0
0
0
8
0
8
% P
% Gln:
0
8
0
0
16
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
8
0
0
0
0
0
0
8
0
% R
% Ser:
16
0
0
24
8
31
0
47
39
0
31
24
8
0
39
% S
% Thr:
0
8
8
0
8
0
0
0
0
8
0
0
0
0
8
% T
% Val:
0
8
0
8
31
24
0
8
0
0
0
0
31
31
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _